Inaccurate use—or omission—of modifiers is one of the top reasons healthcare providers and medical billing companies face costly claim denials. Modifiers GA, GX, GY, and GZ are especially important because they determine whether Medicare or patients are financially responsible for services. GA applies when an Advance Beneficiary Notice (ABN) is issued for services Medicare may deny, while GX covers voluntary ABNs for services Medicare excludes. GY indicates services that are statutorily excluded, and GZ applies when no ABN is issued, leaving providers liable. Misuse of these modifiers can lead to payment delays, compliance risks, and lost revenue. By applying them correctly, providers ensure claims are processed smoothly, liability is properly assigned, and patients understand their financial responsibility. At Allzone MS, we help practices avoid denials, stay Medicare compliant, and safeguard revenue through accurate billing and expert denial management solutions.