When you encounter Error 6010 100, QuickBooks cannot connect to your company file, usually due to interference from external programs or corrupted QuickBooks components. To fix it, verify that no antivirus software is blocking QuickBooks processes, and check the hosting settings to ensure only the server computer hosts the file. Running QuickBooks File Doctor can also repair file corruption. Solving this error quickly is important because unresolved company file issues can lead to productivity delays and possible data inconsistencies.