Spermidine: How Systemic and Topical Administration of Spermidine Accelerates Skin Wound Healing
Autophagy is particularly important in wound healing because skin repair requires the removal of damaged cells and the generation of new, healthy tissue. By stimulating autophagy, spermidine enhances the skin’s ability to regenerate after injury. This biological mechanism forms the foundation for understanding how systemic and topical administration of spermidine accelerates skin wound healing. Whether delivered internally through supplementation or applied externally to the skin, spermidine influences the fundamental processes that drive tissue repair.